1. 癌症之訊息傳遞與標靶治療

2. 癌症與粒線體之關聯性探討

1. 主要學歷：

Kaohsiung Medical College, Taiwan MD in Medicine, 1981

Mayo Graduate School, Mayo Clinic, Rochester, MN Ph.D. in Experimental Pathology, 1989

2. 經歷：

1983-1984 Resident, Department of Internal Medicine, Chang Gung Memorial Hospital, Taiwan

1984-1985 Resident, Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan

1985-1989 Graduate Student, Experimental Pathology, Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA

1989 Postdoctoral Fellow, Department of Molecular Biology and Biochemistry, Mayo Clinic, Rochester, Minnesota, USA

1989-1997 Assistant Professor, Department of Pathology, University of Tennessee, Memphis, Tennessee, USA

1997-present Senior Pathologist, Department of Pathology, Mackay Memorial Hospital

3. 現職：

馬偕醫院病理科主任

馬偕醫院醫學研究部癌症研究組組長

馬偕醫院醫學研究部微生物組組長

台灣分子醫學會理事長

黃玉文、

黃榮達、

吳竺燕

 

1. Su YW, Huang YW, Chen SH, and Tzen CY*. Quantitative analysis of plasma HBV DNA for early evaluation of the response to transcatheter arterial embolization for HBV-related hepatocellular carcinoma. World J Gastroenterol. 2005;11:6193-6196.
2. Tzen CY* and Wu TY. Evolutional analysis in determining pathogenic versus nonpathogenic mutations of ATPase 6 in human mitochondriopathy. Ann NY Acad Sci. 2005;1042:19-24. {SCI}
3. Tzen CY*, Mau BL, Huang YW, Huang MJ and Chen CP. Is extramedullary plasmacytoma an oligoclonal tumor with clonal selection during tumor progression? Histopathology. 2006;48:469-471. {SCI}
4. Tzen CY, Wu TY, and Tzen CY*. Detection of Mycobacteria in Crohn’s disease by a broad spectrum polymerase chain reaction. J Formos Med Assoc. 2006;105:290-298. {SCI}
5. Tzen CY*, Mau BL, and Hsu HJ. Analysis of disease-associated ND4 mutations: How do we know which mutation is pathogenic? Mitochondrion. 2007;7:151-156. {SCI}
6. Wang HM, Huang YW, Huang JS, Wang CH, Kok VC, Hung CM, Chen HM, and Tzen CY*. Anaplastic carcinoma of the thyroid arising more often from follicular carcinoma than papillary carcinoma. Ann Surg Oncol. 2007;14:3011-3018. {SCI}
7. Tzen CY, Wang JH, Huang YJ, Wang MN, Lin PC, Lai GL, Wu CY, and Tzen CY*. Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses. Dig Dis Sci. 2007;52:792-797. {SCI}
8. Tzen CY* and Mau BL. Analysis of CD117-Negative Gastrointestinal Stromal Tumors. World J Gastroenterol. 2005;11:1052-1055.
9. Tzen CY*, Huang YW, and Wang MN. Cloning of Genes Expressed in Cell Quiescence: A New Function of the ras-Recision/Lysyl Oxidase Gene. Chin J Physiol. 2007;50:57-62. {SCI}
10. Tzen CY*, Wu CJ, Huang ZD, and Wu TY. Poorly differentiated transitional cell carcinoma versus leiomyosarcoma of the ureter: different defects in tumor suppressor genes. Histopathology. 2007;51:271-273. {SCI}
11. Tzen CY*, Wang MN, and Mau BL. Spectrum and Prognostication of KIT and PDGFRA Mutation in Gastrointestinal Stromal Tumors. Eur J Surg Oncol. 2007. (in press) {SCI}
12. Lim KH, Huang MJ, Chen LT, Wang TE, Liu CL, Chang CS, Liu MC, Hsieh RK, and Tzen CY*. Molecular analysis of secondary kinase mutations in imatinib-resistant gastrointestinal stromal tumors. Med Oncol. 2007. (in press) {SCI}
    

國科會

a. 95年 專題研究計畫 (一般型研究計畫) 粒腺體突變在贅生性轉形中的意義 (2/2)

b. 94年 專題研究計畫 (一般型研究計畫) 粒腺體突變在贅生性轉形中的意義 (1/2)

c. 93年 專題研究計畫 (一般型研究計畫) Dermatopontin為乳癌疑抑瘤基因之研究 (3/3)

d. 92年 專題研究計畫 (一般型研究計畫) Dermatopontin為乳癌疑抑瘤基因之研究 (2/3)

e. 91年 專題研究計畫 (一般型研究計畫) Dermatopontin為乳癌疑抑瘤基因之研究 (1/3)

院內競爭力計畫

粒腺體醫學 93年至今

1. DHPLC
2. PCR
3. CCD影像處理系統
4. 高速微量冷凍離心機
5. CO2 incubator
6. 雜交反應烘箱
7. 倒立螢光顯微鏡
8. 高壓滅菌鍋