NAME: 鄭仁坤, Jen-Kun Cheng, MD, PhD.
BIRTH DATE: April. 24, 1964.
E-mail: jkcheng@usa.net
EDUCATION and TRAINING
July 1983-June 1990, Young Min Medical College M.D., Taipei, Taiwan
July 1990-May 1992, Military service, Acupuncture practice
July 1992-July 1996, Residency, Department of Anesthesiology, Mackay Memorial Hospital, Taipei, Taiwan
August 1998- July 1999, Research Fellow, Department of Anesthesiology, Wake Forest University School of Medicine, North Carolina, USA
July 2001-June 2005, Institute of Pharmacology, College of Medicine, National Taiwan University, PhD.
April 18-21, 2006, Preceptorship (ultrasound guided regional anesthesia), Toronto Western Hospital, Canada.
April 22-26, 2006, Workshop (International Society of Ultrasound and Regional Anesthesia, ISURA), Toronto, Canada.
POSITION
August 1996-now, Staff Anesthesiologist, Department of Anesthesiology, Mackay Memorial Hospital, Taipei, Taiwan.
2000-2005, Lecturer, Department of Anesthesiology, Taipei Medical University, Taipei, Taiwan.
2006-now, Assistant Professor, Department of Anesthesiology, Taipei Medical University, Taipei, Taiwan.
2006-now, Assistant Professor, Department of Medicine, National Yang-Ming University, Taipei, Taiwan.
CERTIFICATION
National Boards of Medical Examiners of R.O.C. # 020173, 1991
Certified, R.O.C. Board of Anesthesiology # 0501, 1996
Acupuncture course training in Veterans General Hospital, Taipei, 1997
Certified, Specialist of Pain Medicine, The Chinese Association for the Study of Pain (IASP Chapter), # 0391, 2002
Certified, Specialist of Cardiac Anesthesia, Taiwan Society of Cardiovascular Anesthesia, # 0024, 2002.
Certified, Instructor for Specialist in Pain Medicine, The Chinese Association for the Study of Pain (IASP Chapter), # 041, 2005
MEMBERSHIPS OF PROFESSIONAL AND SOCIETIES
R.O.C. Board of Anesthesiologists
Taiwan Medical Association
Taipei County Medical Association
Chinese Association for the Study of Pain
Society of Emergency & Critical Care Medicine, Taiwan.
Society for Modern Acupuncture Research
American Society of Anesthesiology
Society for Neuroscience
International Association for the Study of Pain
FIELD of SPECIALTY:
Pain research in animal models, Ultrasound guided regional anesthesia.
MAJOR AWARDS and HONORS:
Young Investigator Award, Chinese Association for the Study of Pain, 2005.
Inaugural member of the International Biographical Centre (IBC) Leading Health Professionals of the World 2006.
Publication List
1. Chia-Shiang Lin, Meei-Ling Tsaur, Chien-Chuan Chen, Chih-Fu Lin, Yuen-Liang Lai,
Jia-Rung Yang, Tien-Chi Hsu, Chen-Hsien Yang, Jen-Kun Cheng*.
Chronic Intrathecal Infusion of Minocycline Prevents the Development of Spinal Nerve
Ligation-induced Pain in Rats. 2006 (Submitted)
2. Jen-Kun Cheng, Chia-Shiang Lin, Jia-Rung Yang, Chien-Chuan Chen, Lih-Chu Chiou.
Spinal Antinociceptive Effects of T-type Calcium Channel Blockers in the Rat Formalin
Test. 2006 (Submitted)
3. Jen-Kun Cheng, Lih-Chu Chiou. Mechanisms of the Antinociceptive Action of
Gabapentin. J Pharmacol Sci 2006;100(5): 471-486. (SCI)
4. Jen-Kun Cheng, Chien-Chuan Chen, Jia-Rung Yang, Lih-Chu Chiou. Antiallodynic
action target of intrathecal gabapentin: Ca2+ Channels, KATP channels or NMDA
receptors? Anesth Analg 2006; Jan;102(1):182-7. (SCI)
5. Hsin-Yi Huang*, Jen-Kun Cheng*, Yang-Shin Shih, Pei-Hsuan Chen, Chin-Lin Wang,
Meei-Ling Tsaur. Expression of A-type K+ channel subunits Kv4.2 and Kv4.3 in rat
spinal lamina II excitatory interneurons and co-localization with pain-modulating
molecules. European Journal of Neuroscience 2005;22(5):1149-57. (*: first authors,
equal contribution, SCI)
6. Chi-Hang Kuok, Jen-Kun Cheng, Kuo-Hwa Wu, Sho-Jen Cheng, Chia-Shiang Lin,
Chun-Jen Huang, Chien-Chuan Chen. Refractory trigeminal neuralgia successfully
treated with gabapentin --- a case report. The Chinese Journal of Pain 2005; 14(2):67-
73.
7. Ying-Lun Chen, Chea-Ying Chen, Jen-Kun Cheng. Delayed tension pneumothorax
during surgery. Journal of the Chinese Medical Association 2005; 68(10):491-4.
8. Wan-Yu Huang, Jen-Kun Cheng, Chea-Ying Chen, Chen-Hsien Yang, Cheng-Kuei
Chang, Chien-Chuan Chen. Successful management of intraoperative sevoflurane-
induced malignant hyperthermia: a case report. Journal of Emergency & Critical Care
Medicine 2005; 16(4):165-174.
9. Jen-Kun Cheng, Ling-Ling Hwang, Robert Chang-Chih Chou, Lih-Chu Chiou.
Analgesic effects of orexins. Journal of Neuropathic Pain & Symptom Palliation 2005;
1(1):47-53.
10. Jen-Kun Cheng, Lee SZ, Yang JR, Wang CH, Liao YY, Chen CC, Chiou LC.
Does gabapentin act as an agonist at native GABAB receptors? J Biomed Sci 2004;
11(3):346-355. (SCI)
11. Rau RH, Li YC, Jen-Kun Cheng, Chen CC, Ko YP, Huang CJ.
Predicting blood pressure change caused by rapid injection of propofol during anesthesia
induction with a logistic regression model. Acta Anaesthesiol Taiwan 2004; 42(2):81-86.
12. Jen-Kun Cheng, Robert Chang-Chih Chou, Ling-Ling Hwang, Lih-Chu Chiou.
Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain. J
Pharmacol Exp Ther 2003; 307(3):1065-1071. (SCI)
13. Jen-Kun Cheng, Yu-Jun Lai, Chien-Chuan Chen, Ching-Rong Cheng, Lih-Chu Chiou.
Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal
gabapentin in a rat model of postoperative pain. Anesthesiology 2003; 98:1472-1479.
(SCI)
14. Lih-Chu Chiou, Kuang-Chieh Chuang, Shu-Huai Fan, Cheng-Hung How, Jen-Kun
Cheng. Does ethanol activate G-protein coupled inwardly rectifying K+ Channels?
Neuroreport 2002; 13(1):163-165. (SCI)
15. Tien-Tien Man, Jen-Kun Cheng, Kar-Lok Wong, Chien-Chuan Chen, Ruey-Horng
Rau,Kuo-Hwa Wu, Ching-Rong Cheng.Tracheal intubation condition--a comparison
between one minute after rocuronium alone, one minute after rocuronium combined with
atracurium and one minute after atracurium with rocuronium at one minute priming
interval. Acta Anaesthesiol Sin 2002 Dec;40(4):179-83.
16. Pei-Shan Tsai, Jen-Kun Cheng, Martin Marsala, Chung-Ren Lin, Gi-Hong Wen, Lin
Ch.Yang. Intrathecal magnesium sulfate attenuates algogenic behavior and spinal amino
acids release after kainic acid receptor activation in rats. Neuroscience Letters 2001;
301:115-118. (SCI)
17. Jen-Kun Cheng, Hui-Lin Pan, James C. Eisenach. Antiallodynic effect of intrathecal
gabapentin and its interaction with clonidine in a rat model of postoperative pain.
Anesthesiology 2000; 92:1126-1131. (SCI)
18. James C. Eisenach, Patricia Lavand’homme, Chuanyao Tong, Jen-Kun Cheng, Hui-Lin
Pan, Raimo Virtanen, Hanna Nikkanen, Robert James. Antinociceptive and hemodynamic
effects of a novel 2-adrenergic agonist, MPV-2426, in sheep. Anesthesiology 1999;
91:1425-1436. (SCI)
19. Jen-Kun Cheng, Mu-His Pan, kuo-Hwa Wu, Martin Saiwong Mok, Tze-TaurWei.
Epidural phenylephrine attenuates hypotension induced by Alkalinized lidocaine epidural
anesthesia. Anesth Analg 1999; 88:1322-6. (SCI)
20. Jen-Kun Cheng, Yin-Lin Chen, Kwok-Kuen Pang, Mu-His Pan, Kuo-Hwa Wu,
Tze-TaurWei :Intraoperative delayed tension pneumothorax after Blunt chest trauma and
positive pressure ventilation: a case report. J Emerg Crit Care Med 8(1):37-42,1997.
21. Ren-Kuen Jen (Jen-Kun Cheng), Kar-Lok Wong, Tze-Taur Wei: Cardiac Arrest
associated with bone cement-A case report and re1ated risk Factors. J. Orthop Surg
ROC12: 352-355, 1995.
22. Jun-Jen Hwang, Yuan-Pi Ko, Ren-Kuen Jen (Jen-Kun Cheng), Yung-Wei Hsu,
Ching-Rong Cheng, Tze-Taur Wei, Ching-Ying Yeh: The use of intranasal nitroglycerine
to prevent pressor responses during intubation in general anesthesia - a comparison of
various doses. Acta Anaesthesiologica Sinica 33(4):205-210,1995.
23. Yuan-Pi Ko, Ching-Rong Cheng, Janne-Chuan Chen, Yung-Wei Hsu, Ren-kuen Jen
(Jen-Kun Cheng),Jun-Jen Hwang, Tze-Taur Wei: A proper size of endotracheal tube for
infant and young child-a retrospective study in Mackay Memorial Hospital Acta
Anaesthesiologica Sinica 33(3):165-171, 1995
24. Janne-Chuan Chen, Ren-kuen Jen (Jen-Kun Cheng), Yung-Wei Hsu, Yuarn-Bih Ke,
Jun-Jen Hwang, Kuo-HwaWu, Tze-Taur Wei : 4P Syndrome(Wolf-Hirschhorn
Syndrome )complicated with Delay onset of Malignant Hyperthemia: a case report. Acta
Anaesthesiologica Sinica 32(4):275-278,1994.
Symposium and Poster Presentations
2006. Sep. 23-24. Annual Meeting of Taiwan Society of Anesthesiologists, Tainan, Taiwan.
Effects of Chronic Intrathecal Infusion of Minocycline on the Development of Spinal Nerve Ligation-induced Pain and Microglial Activation in Rats (Poster, first author)
Continuous Intrathecal Ethosuximide Prevent the Development of Thermal Hyperalgesia, but not Tactile Allodynia, in L5/6 Spinal Nerve Ligation Neuropathic Pain Model (Poster, first author, supported by NSC 94-2314-B-195-006)
Chronically Infused Intrathecal Gabapentin in Rats (Poster, first author)
Ultrasound-guided Regional Nerve Block (Workshop instructor: Phantom Device Simulation)
2006. Aug. 20. 急重疼痛醫學陷阱與治療研討會 (臺灣老人急重症醫學會主辦), Taipei 急重疼痛生理机轉與治療新趨勢 (Speaker)
2006. Mar. 18-19. Annual Meeting of Taiwan Pain Society, Kaohsiung, Taiwan.
The effect of continuous intrathecal minocycline on the development of spinal nerve ligation-induced pain behaviors in rats. (Poster, first author)
2005. Nov. 12-16, Annual Meeting of the Society for Neuroscience in Washington DC, USA.
Analgesic effects of intrathecal mibefradil, ethosuximide and nickel in the rat formalin test (Poster, first author, supported by NSC 93-2314-B-195-024)
2005, Sep. Annual Meeting of Taiwan Society of Anesthesiologists in Taipei, Taiwan.
The possible involvement of N-type Ca2+ channel ��2��-1 subunit in the antiallodynic effect
of intrathecal gabapentin in the postoperative pain model (Poster, first author)
2005, Mar. Annual Meeting of Taiwan Pain Society in Tainan, Taiwan.
Neurotoxicity study of continuous intrathecal infusion of gabapentin (Poster, first author)
2004. Oct. 23-27, Annual Meeting of the American Society of Anesthesiologists, Las Vegas, USA.
Antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or NMDA receptors? (Poster, first author, supported by NSC92-2314-B-195-018)
2004. Sep. 25-26, 台灣麻醉醫學會年會
Comparative cardiotoxicity of R(+)- and S(-)-bupivacaine (Workshop speaker)
The effectiveness of preoperative radiotherapy on mediastinal tumor-induced tracheal compression and successful anesthetic management of tumor biopsy – case report (Poster, second author)
2004. Apr. 10-11, 中華民國93年度第19屆生物醫學聯合學術年會
Antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or
NMDA receptors? (Poster, first author, supported by NSC92-2314-B-195-018)
A novel Trp3985Arg mutation in the ryanodine receptor (RYR1) gene in a Taiwanese patient with malignant hyperthermia (Poster, first author)
2003. Nov. 9, Annual Meeting of Society for Neuroscience, New Orleans, Louisiana, USA.
Gabapentin Fails to Activate GABAB Receptors in Periaqueductal Gray Slices (Poster, second author, supported by NSC 91-2314-B-195-027)
2003. Oct. 28, Invited Speaker, Symposium: Clinical Management of Neuropathic Pain. Kaoshiong, Taiwan.
“Possible mechanism(s) of antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain”
2003. Oct. 14, Annual Meeting of the American Society of Anesthesiologists in San Francisco.
GABAB Receptor is not the Target of the Antiallodynic Effect of Intrathecal Gabapentin in a Rat Model of Postoperative Pain (Poster, first author, supported by NSC 91-2314-B-195-027)
2003. Sep. 20, 台灣麻醉醫學會年會
Successful Anesthetic Management of Malignant Hyperthermia During Consecutive Neurosurgeries – a Case Report (Poster, third author)
Predicting blood pressure change caused by rapid injection of propofol during anesthesia induction- using logistic regression model (Poster, fourth author)
2003. Mar.22-23, 中華民國92年度第18屆生物醫學聯合學術年會
GABAB receptor is not the target of the antiallodynic effect of intrathecal gabapentin (Poster, first author, supported by NSC 91-2314-B-195-027)
Gabapentin is not a GABAB receptor agonist in periaqueductal gray slices (Poster, second author, supported by NSC 91-2314-B-195-027)
Intrathecal orexins reduce incision-induced allodynia in a rat model of postoperative pain (Poster, third author)
2002. Sep. 7, Annual Meeting of the Society of Anesthesiologists of Republic of China.
Intrathecal epinephrine decreases the dosage of spinal bupivacaine for total knee replacement (Poster, second author)
2002. Jul. 27, Refresh course of Chinese Association for the Study of Pain, Taiwan
The possible analgesic mechanism of intrathecal gabapentin in animal pain model (Speaker)
2001. Nov. 13, Annual Meeting of Society of Neuroscience in San Diego
Coadministration with magnesium chloride attenuates the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain (Poster, first author, supported by NSC 89-2314-B-195-016)
2001. Sep. Annual Meeting of the Society of Anesthesiologists of Republic of China
The mechanism of antinociceptive effect of intrathecal gabapentin - possible involvement of calcium channel 2 subunit (Speaker)
2001. Aug. 18, Symposium: Management and Application of Local Anesthetics
Local infiltration with 0.5% ropivacaine and ketorolac in hemorrhoidectomy – preliminary experience (Speaker)
2000. Sep. 16, Annual Meeting of the Society of Anesthesiologists of Republic of China.
Skin Temperature changes of dermatome L4-5, L1 and T10 during epidural anesthesia (Poster, first author)
1999. Dec. 12, Annual Meeting of the American Society of Anesthesiologists
Analgesia from intrathecal gabapentin in a rat model of postoperative pain (Poster, first author)
Renew:2006/08/01
