乳癌常見處方

Disease	Regiment		Frequency	Note
Breast Ca	Adjuvant setting
	CMF(IV)	Cyclophosphamide 600 mg/m^2 IV D1 Methotrexate 40 mg/m^2IV D1,8 5-Flurouracil 600 mg/m^2 IV D1,8	Repeat cycle every 21 days
	CMF(PO)	Cyclophosphamide 100 mg/m^2 PO D1-14 Methotrexate 40 mg/m^2IV D1,8 5-Flurouracil 600 mg/m^2 IV D1,8	Repeat cycle every 21 days
	CAF	Cyclophosphamide 600 mg/m^2 IV Doxorubicin 60 mg/m^2 IV 5-Flurouracil 600 mg/m^2 IV	Repeat every 21 days
	FEC	5-Flurouracil 500 mg/m^2 IV Epirubicin 100 mg/m^2 IV Cyclophosphamide 500 mg/m^2 IV	Repeat every 21 days
	AC	Doxorubicin 60 mg/m^2 IV Cyclophosphamide 600 mg/m^2 IV	Repeat cycle every 21 days
	AC + Taxo Indication: (1) Node positive, and (2) ER (-) and PR (-)	Doxorubicin 60 mg/m^2 IV Cyclophosphamide 600 mg/m^2 IV Followed by: Palitaxel 175 mg/m^2 IV on day1	Repeat cycle every 21 days for 4 cycles
			Repeat cycle every 21 days for 4 cycles
	TAC Indication: Node positive (especially for node 1~3)	Doxotaxel 75 mg/m^2 IV Doxorubicin 50 mg/m^2 IV Cyclophosphamide 500 mg/m^2 IV	Repeat cycle every 21 days	Needs G-CSF Support
Breast Ca	Metastatic setting
	FAC	5-Flurouracil 500 mg/m^2 IV on D1,8 Doxorubicin 50 mg/m^2 IV D1 Cyclophosphamide 500 mg/m^2 IV D1	Repeat every 3-4 weeks
	TAC	Doxotaxel 75 mg/m^2 IV Doxorubicin 50 mg/m^2 IV Cyclophosphamide 500 mg/m^2 IV	Repeat every 21 days
	Gemcitabine + Taxol	Gemcitabine 1,250 mg/m^2 IV on D1,8 Paclitaxel 175 mg/m^2 IV on D2	Repeat every 21 days
	Capecitabine	2,000-2,500 mg/m^2 PO daily in two divided doses, for 14 days	Repeat cycle after 7-days rest
	Vinorelbine	15-25 mg/m^2 IV infusion weekly, for 4-6 weeks	Repeat cycle after 1-2 weeks rest
	Trastuzumab Indication: Her2-neu amplification: FISH (+), or Her2-neu overexpression: IHC (+++)