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胸腔外科

  • 詹梅麟醫師相片

    詹梅麟

    主任

    胸腔外科 :
    台北門診掛號  淡水門診掛號

    詹梅麟醫師本頁二維碼

  • 現職

      馬偕胸腔外科主任、馬偕醫學大學兼任臨床副教授、馬偕醫學大學生物醫學研究所部定助理教授、台灣胸腔外科醫學會理事、台灣胸腔暨心臟血管外科醫學會監事


    主要學歷

      高學醫學大學醫學系(MD)、陽明交通大學傳統醫學研究所博士班(PHD)


    主要經歷

      高雄醫學大學畢業



      埔里榮民醫院外科住院醫師



      台北榮民總醫院外科住院醫師、總醫師及主治醫師



      加拿大多倫多總醫院Latner Thoracic Laboratory腫瘤免疫學研修醫師



      加拿大多倫多總醫院肺臟移植臨床訓練觀察員



      馬偕紀念醫院主治醫師(2012年迄今)


    其他相關

      台灣外科醫學會



      台灣胸腔暨心臟血管外科醫學會（指導醫師）



      台灣胸腔外科醫學會（指導醫師）



      台灣胸腔暨重症加護醫學會



      中華民國重症醫學會


主治項目或專長

胸腔達文西機械手臂手術、胸腔內視鏡微創手術、一般胸腔外科疾病(氣胸、膿胸、吞嚥困難、胸痛)、肺癌、食道癌、縱隔腔腫瘤、手汗症、橫膈膜疾病、胸壁腫瘤、胸壁畸形矯正、胸腔內視鏡手術、甲狀腺腫大、胸腔外傷


論文研究

    2. Hua-Chen Chan, Hsiu-Chuan Chan, Liu-Fang Wang, Mei-Lin Chan(詹梅麟）, Wen-Chien Huang, Daniel Bender, Yu-Min Ko, Ming-Lung Yu, Guan-Ming Ke, Mei-Chuan Chou, Ching-Kuan Liu , Liang-Yin Ke (2026, Jun). The lysophosphatidylcholine-HIF-1α axis enhances apolipoprotein E sialylation and promotes electronegative LDL accumulation. iScience , 29(6):116167.
    4. Yi-Wen Huang, Hua-Chen Chan, Jing-Yi Khoo, Mei-Lin Chan(詹梅麟）, Daniel Bender, Vinoth Kumar Ponnusamy, Abdel Ali Belaidi, Liang-Yin Ke (2025, Dec). Assessing the critical role of ceramide in the pathogenesis of Alzheimer's disease and its clinical significance . Neurochemistry International .
    6. Shao-Chi Hung, Chih-Chieh Chen, Hua-Chen Chan, Mei-Lin Chan(詹梅麟), You Shan Ngui, Jia-Bin Mei, Yi-Wen Huang, Vyala Hanumanthareddy Chaithra, Gopal Kedihithlu Marathe, Liang-Yin Ke (2025, Oct). Structural and molecular dynamics insights into the competitive inhibition of the platelet-activating factor receptor by acyl-PAF. Journal of Biological Chemistry.
    8. Ping-Tsung Yu, Sheng Hsiung Yang, Hui-Hsuan Shih, Wei Ming Huang, Jie-Yang Jhuang, Mei-Lin Chan(詹梅麟), Wen-Chien Huang (2025, Sep). Archimedes navigation system-guided bronchoscopic trans-parenchymal nodule access for peripheral lung nodules: a single-center experience. Frontiers in Oncology . 本人為通訊作者.
    10. James Mei-Lin Chan(詹梅麟), Yuan-Ching Chang, Hua-Chen Chan, Hsiu-Chuan Chan, Wei-Chin Chang, Liu-Fang Wang, Tung-Hu Tsai, Yu-Jen Chen and Wen-Chien Huang (2024, Oct). FK228 suppress the growth of human malignant pleural mesothelioma tumor independent to epithelioid or non-epithelioid histology . Molecular Medicine, 30: 73. 本人為第一作者.
    12. Shao-Chi Hung, Te-Fu Chan, Hsiu-Chuan Chan, Chia-Ying Wu, Mei-Lin Chan(詹梅麟), Jie-Yang Jhuang, Ji-Qin Tan, Jia-Bin Mei, Shi-Hui Law, Vinoth Kumar Ponnusamy, Hua-Chen Chan, Liang-Yin Ke (2024, Aug). Lysophosphatidylcholine Impairs the Mitochondria Homeostasis Leading to Trophoblast Dysfunction in Gestational Diabetes Mellitus. Antioxidants (Basel).
    14. Tung-Yu Tiong, Mei-Lin Chan(詹梅麟), Chun-Hua Wang, Vijesh Kumar Yadav, Narpati Wesa Pikatan, Iat-Hang Fong , Chi-Tai Yeh, Kuang-Tai Kuo, Wen-Chien Huang (2023, Sep). Exosomal miR-21 determines lung-to-brain metastasis specificity through the DGKB/ERK axis within the tumor microenvironment. Life Science , 329:121945.
    16. Licun Wu, Mikihiro Kohno, Junichi Murakami, Amin Zia, Jonathan Allen, Hana Yun, Meilin Chan(詹梅麟), Cristina Baciu, Mingyao Liu, Veronique Serre-Beinier, Michele De Palma, Emanuela Felley-Bosco, Jonathan Yeung, Trevor J Pugh, Marc de Perrot (2023, Feb). Defining and targeting tumor-associated macrophages in malignant mesothelioma. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 120(9):e2210836120.
    18. Nai-Wen Su, Lai-Man Mok, Mei-Lin Chan(詹梅麟), Hung-Chang Liu, Wei-Chin Chang, Chun-Ho Yun, Tze-Yu Shieh, Ming-Che Wu, Huan-Chau Lin, Wen-Chien Huang and Yu-Jen Chen. (2023, Feb). Impact of Perineural Invasion and Preexisting Type 2 Diabetes on Patients with Esophageal Squamous Cell Carcinoma Receiving Neoadjuvant Chemoradiotherapy. Cancers , 15(4): 1122.
    20. Mei-Lin Chan(詹梅麟), Licun Wu, Zhihong Yun, Trevor D. McKee, Michael Cabanero, Yidan Zhao, Mikihiro Kohno, Junichi Murakami & Marc de Perrot (2021, Jul). Blocking the GITR-GITRL pathway to overcome resistance to therapy in sarcomatoid malignant pleural mesothelioma. communications biology , 26;4(1):914. 本人為第一作者.
    22. Junichi Murakami, Licun Wu, Mikihiro Kohno, Mei-Lin Chan (詹梅麟), Yidan Zhao, Zhihong Yun, B C John Cho, Marc de Perrot (2021, Apr). Triple-modality therapy maximizes antitumor immune responses in a mouse model of mesothelioma. Sci Transl Med, 13(589):eabd9882.
    24. Mikihiro Kohno, Junichi Murakami, Licun Wu, Mei-Lin Chan (詹梅麟), Zhihong Yun, B C John Cho, Marc de Perrot (2020, Nov). Foxp3 + Regulatory T Cell Depletion after Nonablative Oligofractionated Irradiation Boosts the Abscopal Effects in Murine Malignant Mesothelioma. J Immunol, 205(9):2519-2531. (SCI, 45/159 in Immunology).
    26. Marc de Perrot, Licun Wu, Michael Cabanero, J Yannis Perentes, Trevor D McKee, Laura Donahoe, Penelope Bradbury, Mikihiro Kohno, Mei-Lin Chan (詹梅麟), Junichi Murakami, Shaf Keshavjee, Ming-Sound Tsao, B C John Cho (2020, May). Prognostic influence of tumor microenvironment after hypofractionated radiation and surgery for mesothelioma. J Thorac Cardiovasc Surg, 159(5):2082-2091. (SCI, 18/210 in Surgery).
    28. Kun-Yao Dai, Yu-Chao Yu, Yi-Shing Leu, Chih-Wen Chi, Mei-Lin Chan (詹梅麟), Chung-Hsin Tsai, Huan-Chau Lin, Wen-Chien Huang, Yu-Jen Chen (2020, Feb). Neoadjuvant Chemoradiotherapy and Larynx-Preserving Surgery for Cervical Esophageal Cancer. J Clin Med, 9(2):387. (SCI, 36/165 in Medicine, General & Internal).
    30. Kun-Yao Dai, Yu-Chao Yu, Yi-Shing Leu, Chih-Wen Chi, Mei-Lin Chan(詹梅麟), Chung-Hsin Tsai,Huan-Chau Lin, Wen-Chien Huang, and Yu-Jen Chen (2020, Feb). Neoadjuvant Chemoradiotherapy and Larynx-Preserving Surgery for Cervical Esophageal Cancer. Journal of Clinical Medicine, 9, 387; doi:10.3390/jcm9020387.
    32. Licun Wu, Irene Dell'Anno, Moshe Lapidot, Yoshitaka Sekido, Mei-Lin Chan (詹梅麟), Mikihiro Kohno, Veronique Serre-Beinier, Emanuela Felley-Bosco, Marc de Perrot (2019, Jun). Progress of malignant mesothelioma research in basic science: A review of the 14th international conference of the international mesothelioma interest group (iMig2018). Lung Cancer , 127:138-145.. (SCI, 12/63 in Respiratory System).
    34. Shi-Hui Law†, Mei-Lin Chan† (詹梅麟), Gopal K Marathe, Farzana Parveen, Chu-Huang Chen, Liang-Yin Ke (2019, Mar). An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases. Int J Mol Sci , 20(5):1149. (SCI, 46/172 in Chemistry, Multidisciplinary). 本人為第一作者.
    36. Licun Wu, Walter Blum, Chang-Qi Zhu, Zhihong Yun, Laszlo Pecze, Mikihiro Kohno, Mei-Lin Chan (詹梅麟), Yidan Zhao, Emanuela Felley-Bosco, Beat Schwaller, Marc de Perrot (2018, Apr). Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma. BMC Cancer , 18(1):471. (SCI, 107/223 in Oncology).
    38. Licun Wu, Walter Blum, Chang-Qi Zhu, Zhihong Yun, Laszlo Pecze, Mikihiro Kohno, Mei-Lin Chan(詹梅麟), Yidan Zhao, Emanuela Felley-Bosco, Beat Schwaller, Marc de Perrot (2018, Apr). Putative cancer stem cells may be the key target to inhibit cancer cell repopulation between the intervals of chemoradiation in murine mesothelioma. BMC Cancer.
    40. Chih-Cheng Hsieh, Yung-Han Sun, Shih-Wei Lin, Yi-Chen Yeh, Mei-Lin Chan (詹梅麟) (2017, May). Surgical outcomes of pulmonary mucoepidermoid carcinoma: A review of 41 cases. PLoS One, 12(5):e0176918. (SCI, 15/64 in Multidisciplinary Science).
    42. Wen-Chien Huang, Mei-Lin Chan (詹梅麟), Ming-Jen Chen, Tung-Hu Tsai, Yu-Jen Chen (2016, Jun). Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related small-molecule inhibitor pterostilbene.. Oncotarget, 7(26):39363-39375. (SCI, 36/213 in Oncology).
    44. Po-Kuei Hsu, Wei-Cheng Lin, Yin-Chun Chang, Mei-Lin Chan (詹梅麟), Bing-Yen Wang, Chao-Yu Liu, Wen-Chien Huang, Chih-Hsun Shih, Chia-Chuan Liu (2015, May). Multiinstitutional analysis of single-port video-assisted thoracoscopic anatomical resection for primary lung cancer. . Ann Thorac Surg, 99(5):1739-44. (SCI, 16/198 in Surgery).
    46. Mei-Lin Chan (詹梅麟), Chih-Cheng Hsieh, Cheng-Wien Wang, Min-Hsiung Huang, Wen-Hu Hsu, Han-Shui Hsu (2011, Nov). Reconstruction after esophagectomy for esophageal cancer: retrosternal or posterior mediastinal route?. J Chin Med Assoc , 74(11):505-10. 本人為第一作者.
    48. Chih-Heng Kuo, Chih-Cheng Hsieh, Mei-Lin Chan (詹梅麟), Anna Fen-Yau Li, Min-Hsiung Huang, Wen-Hu Hsu, Han-Shui Hsu (2011, Feb). Small cell carcinoma of the esophagus: a report of 16 cases from a single institution and literature review. Ann Thorac Surg, 91(2):373-8. (SCI, 11/188 in Surgery).