電子顯微鏡研究組

組長   陳冬英 醫師

研究人員

楊誠修 醫檢師、尤心佑 研究助理

1. 支援病理科腎臟切片、心臟切片、肌肉切片、皮膚切片、毛髮疾病與特殊癌症鑑別診斷。
2. 支援病理科移植排斥診斷。
3. 提供醫學研究部各實驗室特定研究主題中TEM或SEM電鏡技術需求並協助照相。
4. 配合生醫發展中心育成廠商需求，提供客制化TEM或SEM電鏡技術服務。

1. 穿透式電子顯微鏡(TEM)：JEM-1400Flash。
2. 掃描式電子顯微鏡(SEM)：HITACHI S-3500N。
   
3. 超薄切片設備：Leica Reichert Ultracut S, Leica EM Trim, Leica RM2065 Microtome等。
4. Sputter Coater：HITACHI E-1030。
5. Vacuum Evaporator：HITACHI VE-1010。
6. Critical Point Dryer：HITACHI HCP-2 。
   

Lin JC, Huang TS, Chen YB, Chen TY, Liu TP, Yang PM. Nedd4 family interacting protein 1 (NDFIP1) is a novel target of PF-429242 in promoting autophagy in hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2026 Jan 1;794:153065. (BIOCHEMISTRY & MOLECULAR BIOLOGY) (IF: 0.63, Ranking= 241/320 =24.8%)

Lin YW, Ting CH, Chen TY, Leu YS. Nasopharyngeal large cell neuroendocrine carcinoma synchronized with nasopharyngeal squamous cell carcinoma: a case report and review of literature. Ear Nose Throat J. 2025 Mar;104(1_suppl):247S-253S. (OTORHINOLARYNGOLOGY) (IF: 0.7, Ranking= 51/67 =24.6%) 

Chou YP, Hsieh LC, Chen TY, Wang YP. Nasal extranodal natural killer/T-cell lymphoma imitating squamous cell carcinoma: a case report. Ear Nose Throat J. 2025 Mar;104(1_suppl):194S-197S. (OTORHINOLARYNGOLOGY) (IF: 0.7, Ranking= 51/67 =24.6%)

Chang YW, Hwang DY, Chen TY, Lin CC, Tseng MH, Tsai JD. Kidney cysts in children with alport syndrome: a report of 3 cases. Kidney Med. 2024 Mar 25;6(5):100815. (UROLOGY & NEPHROLOGY) (IF. 1.11, Ranking= 25/133 =81.6%)

Jiang JY, Leu YS, Wang YP, Chan YK, Chen TY. A giant schwannoma extending from medial portion of middle cranial fossa to parapharyngeal space and deep parotid space. Ear Nose Throat J. 2024 Dec;103(12):NP710-NP713. (OTORHINOLARYNGOLOGY) (IF: 0.7, Ranking= 51/67 =24.6%)

Wu JC, Chen TY, Wen-Chien H, Lee JJ, Chen CH. Lipid pneumonia mimicking lung cancer in a middle-age woman. Ann Thorac Cardiovasc Surg. 2024;30(1):24-00117. (SURGERY) (IF: 1.1, Ranking =196/292=67.1%)

Lin JC, Liu TP, Chen YB, Huang TS, Chen TY, Yang PM. Inhibition of CDK9 exhibits anticancer activity in hepatocellular carcinoma cells via targeting ribonucleotide reductase. Toxicol Appl Pharmacol. 2023 Jul 15;471:116568. (PHARMACOLOGY & PHARMACY) (IF: 3.3, Ranking =119/354=33.6%)

Liu TL, Lin SP, Zenker M, Chen TY, Chang JH, Lin CC, Tsai JD. X-linked recessive galloway-mowat syndrome 2 caused by a specific LAGE3 variant. Pediatr Neonatol. 2023 Mar;64(2):208-209. (PEDIATRICS) (IF: 2.3, Ranking =53/186=28.4%)

Chen TY, Yang HW, Lin DS, Huang ZD, Chang L. HIV fragments detected in Kaposi sarcoma tumor cells in HIV-infected patients. Medicine (Baltimore). 2022 Oct 28;101(43):e31310. (MEDICINE, GENERAL & INTERNAL) (IF: 1.4, Ranking =141/329=42.8%)