重症醫學科

李士毅

主治醫生
現職
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主治項目或專長

論文研究

Published Articles – Original Articles (* corresponding author)
1. Shih-Yi Lee, Shao-Tung Wu, Chen-Xuan Du, Hui-Chun Ku. Potential Role of Dipeptidyl Peptidase-4 in Regulating Mitochondria and Oxidative Stress in Cardiomyocytes. Cardiovasc Toxicol. 2024 Oct;24(10):1090-1104. (IF: 3.3; First author)
2. Cheng-Wei Huang, Shih-Yi Lee*, Chen-Xuan Du, Shao-Tung Wu, Yueh-Hsiung Kuo, Hui-Chun Ku. Caffeic acid ethanolamide induces antifibrosis, anti-inflammatory, and antioxidant effects protects against bleomycin-induced pulmonary fibrosis. Biomed Pharmacother. 2024 Apr:173:116298. (IF: 7.5; *co-first author)
3. Shih-Yi Lee, Yueh-Hsiung Kuo, Chen-Xuan Du, Cheng-Wei Huang, Hui-Chun Ku. A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodeling. Biomed Pharmacother. 2023;162:114709. (IF: 7.5; *co-first author)
4. Hui-Chun Ku, Cheng-Wei Huang, Shih Yi Lee*. Technical refinement of a bilateral renal ischemia–reperfusion mouse model for acute kidney injury research. J Vis Exp. 2023; 3(201). doi: 10.3791/63957. (IF: 1.424; *corresponding author)
5. Cheng-Wei Huang, Shih-Yi Lee*, Chen-Xuan Du, Hui-Chun Ku. Soluble dipeptidyl peptidase-4 induces epithelial-mesenchymal transition through tumor growth factor-beta receptor. Pharmacol Rep. 2023;75(4):1005-1016. (IF: 4.5; *corresponding author)
6. Shih-Yi Lee, Yueh-Hsiung Kuo, Chen-Xuan Du, Cheng-Wei Huang, Hui-Chun Ku. A novel caffeic acid derivative prevents angiotensin II-induced cardiac remodeling. Biomedicine & Pharmacotherapy 2023; 162: 114709. (IF: 7.5; First author)
7. Wei-Hsiang Liao, Shih-Yi Lee*, En-Chih Liao, Wen-Han Chang, Tse-Hao Chen, Ming-Kun Huang , Jui-Ping Lin, Weide Tsai , Fang-Ju Sun, Ding-Kuo Chien. A pilot study of digital bedside cards in the emergency room of a medical centre in Taiwan. Scientific Reports 2023; 13: 6965 (IF: 4.997; *co-first author)
8. Hui-Chun Ku, Ding-Kuo Chien, Chuan-Lei Chao, Shih-Yi Lee*. Left anterior descending coronary artery ligation for ischemia-reperfusion research: Model Improvement via Technical Modifications and Quality Control. J Vis Exp. 2022; 16: (190). doi: 10.3791/63921. 4 (IF: 1.424; *corresponding author)
9. Cheng-Wei Huang, Shih-Yi Lee*, Tzu-Tang Wei, Yueh-Hsiung Kuo, Shao-Tung Wua, Hui-Chun Ku. A novel caffeic acid derivative prevents renal remodeling after ischemia/ reperfusion injury. Biomedicine & Pharmacotherapy 142 (2021) 112028. (IF: 7.5; *co-first author)
10. Yu-Ling Weng, Chin-Chia Liang, Chie-Chien Tseng, Shih-Yi Lee, Gwo-Liang Yeh. A Survey of PM2.5 Preventive Behavioral Intention and Related Factors among Community Elderly in Northern Taiwan. Medicine (Baltimore). 2021 Jul 23; 100(29): e26675. (IF: 2.0, Q2)
11. Hwee-Kheng Lim, Shih-Yi Lee*, Che-Wei Wu, Jerry Cheng-Yen Lai, Yueh-Hsiu Ho, Hui-Chun Ku. Comparative study between oral acetaminophen and lidocaine spray on endotracheal tube-related sore throat in adult intensive care. Signa Vitae 2021; 1-6. (IF: 1.1; *co-first author)
12. Shih-Yi Lee, Shao-Tung Wu, Yao-Jen Liang, Ming-Jai Su, Cheng-Wei Huang, Yu-Hsuan Jao, Hui-Chun Ku. Soluble dipeptidyl peptidase-4 induces fibroblast activation through proteinase-activated receptor-2. Frontiers in Pharmacology. 2020;11:552818. (IF: 5.988; First author)
13. Wei-Hsiang Liao, Shih-Yi Lee*, En-Chih Liao, Wen-Han Chang, Tse-Hao Chen, Ming-Kun Huang , Jui-Ping Lin, Weide Tsai , Fang-Ju Sun, Ding-Kuo Chien. A pilot study of digital bedside cards in the emergency room of a medical centre in Taiwan. Scientific Reports 2023; 13: 6965 (IF: 4.997; *co-first author)
14. Hui-Chun Ku, Ding-Kuo Chien, Chuan-Lei Chao, Shih-Yi Lee*. Left anterior descending coronary artery ligation for ischemia-reperfusion research: Model Improvement via Technical Modifications and Quality Control. J Vis Exp. 2022; 16: (190). doi: 10.3791/63921. 4 (IF: 1.2; *corresponding author)
15. Cheng-Wei Huang, Shih-Yi Lee*, Tzu-Tang Wei, Yueh-Hsiung Kuo, Shao-Tung Wua, Hui-Chun Ku. A novel caffeic acid derivative prevents renal remodeling after ischemia/ reperfusion injury. Biomedicine & Pharmacotherapy 142 (2021) 112028. (IF: 7.5; *co-first author)
16. Hwee-Kheng Lim, Shih-Yi Lee*, Che-Wei Wu, Jerry Cheng-Yen Lai, Yueh-Hsiu Ho, Hui-Chun Ku. Comparative study between oral acetaminophen and lidocaine spray on endotracheal tube-related sore throat in adult intensive care. Signa Vitae 2021; 1-6. (IF: 1.1; co-first author)
17. Shih -Yi Lee, Shao-Tung Wu, Yao-Jen Liang, Ming-Jai Su, Cheng-Wei Huang, Yu-Hsuan Jao, Hui-Chun Ku. Soluble dipeptidyl peptidase-4 induces fibroblast activation through proteinase-activated receptor-2. Frontiers in Pharmacology. 2020;11:552818. (IF: 5.988; First author)
18. Sathishkumar Chinnapaiyana, Tse-Wei Chen, Shen-Ming Chen, Z. Abdullah Alothman, M. Ajmal Ali, S.M. Wabaidur, Fahad Al-Hemaid, Shih-Yi Lee*, Wen-Han Chang. Ultrasonic-assisted Preparation and Characterization of Magnetic ZnFe2O4/g-C3N4 Nanomaterial and their Applications towards Electrocatalytic Reduction of 4-Nitrophenol. Ultrasonics Sonochemistry 2020; 67: 105071. (IF: 9.366; *corresponding author)
19. Tse-Wei Chen, Umamaheswari Rajaji, Shen-Ming Chen, Jun-Yu Wang, Zeid Abdullah Alothman, M. Ajmal Ali, Mohamed Wabaidur, Fahad Al-Hemaid, Shih-Yi Lee*, Wen-Han Chang. Sonochemical preparation of carbon nanosheets supporting cuprous oxide architecture for high-performance and non-enzymatic electrochemical sensor in biological samples. Ultrasonics Sonochemistry 2020; 66: 105072. (IF: 9.366; *corresponding author)
20. Tse-Wei Chen, Sathishkumar Chinnapaiyan, Shen-Ming Chen, M. Ajmal Ali, Mohamed Soliman Elshik, Shih-Yi Lee*, Wen-Han Chang, Ahmed Hossam Mahmoud. Sonochemical approach to the synthesis of metal tungstate/nafion composite with electrocatalytic properties and its electrochemical sensing performance. Ultrasonics Sonochemistry 2020; 66: 104901. (IF: 9.366; *corresponding author)
21. Bhuvanenthiran Mutharani, Murugan Keerthi, Shen-Ming Chen, Palraj Ranganathan, Tse-Wei Chen, Shih-Yi Lee*, and Wen-Han Chang. One-Pot Sustainable Synthesis of Ce2S3/Gum Arabic Carbon Flowers Nanocomposite for the Detection of Insecticide Imidacloprid. ACS Appl Mater Interfaces. 2020;12(4):4980-4988. (IF: 10.383; *corresponding author)
22. Ding-Kuo Chien, Shih-Yi Lee, Chung-Lieh Hung, Fang-Ju Sun, Mau-Roung Lin, Wen-Han Chang. Do patients with non-ST-elevation myocardial infarction without chest pain suffer a poor prognosis? Taiwanese Journal of Obstetrics & Gynecology 58 (2019) 788-792. (IF: 1.705, Q3)
23. Tse-Wei Chena, Umamaheswari Rajaji, Shen-Ming Chen, Bih-Show Lou, Nabil Al-Zaqri, Ali Alsalme, Fahad A. Alharthie, Shih-Yi Lee*, Wen-Han Chang. A sensitive electrochemical determination of chemotherapy agent using graphitic carbon nitride covered vanadium oxide nanocomposite; sonochemical approach. Ultrasonics Sonochemistry 2019; 58, 104664. (IF: 9.366; *corresponding author)
24. Shih-Yi Lee, Ling-Wei Hsin, Ming-Jai Su, Ching-Chia ChangChien, Hui-Chun Ku. A novel isoquinoline derivative exhibits anti-inflammatory properties and improves the outcomes of endotoxemia. Pharmacological Reports 2019;71: 1281–1288. (IF: 3.027; First author)
25. Alagumalai Krishnapandi, Ramachandran Rajakumaran, Shen-Ming Chen, Yi-Ling, Li, Tse-Wei Chen, Shih-Yi Lee*,Wen-Han Chang. Facile synthesis of zinc cobaltate nano flakes: an enhanced electrochemical detection of organic pollutant 4-nitrotoluene. Int. J. Electrochem. Sci. 2019; 14: 8058 – 8069. (IF: 1.765; *corresponding author)
26. Vengudusamy Renganathan, Ragu Sasikumar, Shen-Ming Chen, Tse-Wei Chen, Syang-Peng Rwei, Shih-Yi Lee*, Wen-Han Chang, Bih-Show Lou. Detection of neurotransmitter (levodopa) in vegetables using nitrogen-doped graphene oxide incorporated nickel oxide modified electrode. Int. J. Electrochem. Sci. 2018; 13: 7206 – 7217. (IF: 1.765; *corresponding author)
27. Shih-Yi Lee, Ding-Kuo Chien, Ming-Yuan Huang, Chien-Hsuan Huang, Shou-Chuan Shih, Kun-Ming Wu, Hui-Chun Ku, Wen-Han Chang. Patient-specific factors associated with difficult mask ventilation in the emergency department. International Journal of Gerontology 2017; 11: 263 – 266. (IF: 0.877; First author)
28. Hui-Chun Ku, Shih-Yi Lee, Shoei-Sheng Lee, Ming-Jai Su. Thaliporphine, an alkaloid from Neolitsea konishii, exerts antioxidant, anti-inflammatory, and anti-apoptotic responses in guinea pig during cardiovascular collapse in inflammatory disease. Journal of Functional Foods 2016; 26: 57–64. (IF: 4.451, Q1)
29. Hui-Chun Ku, Shih-Yi Lee, Kai-Chien Yang, Yueh-Hsiung Kuo, Ming-Jai Su. Modification of caffeic acid with pyrrolidine enhances antioxidant ability by activating AKT/HO-1 pathway in heart. PLoS ONE 2016; 11(2): e0148545. (IF: 3.240, Q2)
30. Shih-Yi Lee, Hui-Chun Ku, Yueh-Hsiung Kuo, Kai-Chien Yang, Ping-Chen Tu, His-Lin Chiu, and Ming-Jai Su. Caffeic acid ethanolamide prevents cardiac dysfunction through sirtuin dependent cardiac bioenergetics preservation. J Biomed Sci 2015; 22:18. (IF:14.5; First author)
31. Shih -Yi Lee, Hui-Chun Ku, Yueh-Hsiung Kuo, His-Lin Chiu, Ming-Jai Su. Pyrrolidinyl caffeamide against ischemia/reperfusion injury in cardiomyocytes through AMPK/AKT pathways. J Biomed Sci 2015; 22:18. (IF:14.5; First author)
32. Ku CH, Lee SY*, Chen CH, Wang YH, Lin CT, Lee SS, Li TH, Su MJ. TM-1-1DP exerts protective effect against myocardial ischemia reperfusion injury via AKT-eNOS pathway. Naunyn-Schmiedebergs Arch. Pharmacol. 2015 May; 388 (5): 539-48. (IF: 3.000; *co-first author)
33. Shih-Yi Lee, Chih-Hao Chen, Kuo-Che Huang, Ching-Ping Hsu, Hui-Chun Ku, Shou-Chuan Shih, Chien-Liang Wu, Fang-Ju Sun, Yueh-Hsiu Ho, Julie Hua-Ying Tai, Yuen-Liang Lai, Wen-Han Chang. Factors associated with the attitude and knowledge toward hospice palliative care among medical caregivers. International Journal of Gerontology 2015; 9: 98-102. (IF: 1.016; First author)
34. Kuo FC, Chiang CL, Shih-Yi Lee, Wu CJ, Chen HH, Chen YW. Complications observed in older new haemodialysis patients in Taiwan. Australas J Ageing 2014; 33(2): 86-92. (IF: 2.111, Q3)
35. Chen CH, Chang H, Shih-Yi Lee, Liu HC, Hung TT, Chen CH, Tai CY. Video-guided tube thoracostomy with use of an electrical nonfiberoptic endoscope. Ann Thorac Surg. 2013; 96(4): 1450-4. doi: 10.1016/j.athoracsur.2013.06.098. (IF: 4.330, Q1)
36. Chen CH, Shih-Yi Lee, Chang H, Liu HC, Hung TT, Chen CH. The adequacy of single-incisional thoracoscopic surgery as a first-line endoscopic approach for the management of recurrent primary spontaneous pneumothorax: a retrospective study. J Cardiothorac Surg. 2012; 29(7): 99. (IF: 1.637, Q3)
37. Chih-Hao Chen, Shih-Yi Lee, Ho Chang, Hung-Chang Liu, Chao-Hung Chen, Wen-Chien Huang. Technical aspects of single-port thoracoscopic surgery for lobectomy. J. Cardiothorac. Surg. 2012, 7: 50. (IF: 1.470, Q4)
38. Shih-Yi Lee, Chien-Liang Wu, Li-Kuo Kuo, Chuan-Tsai Lai, Ching-Ping Hsu, Hwung-Ying Hwung, Yu-Wei Chen, Yueh-Hsiu Ho, Hui-Chuan Hsu, Fang-Ju Sun, Ping-Fang Yuan, Ivy Pan, Wen-Han Chang. The effects of xylocaine spray for pain control caused by endotracheal tube in critical care. International Journal of Gerontology 2012; 6(1):11-15. (IF: 1.016; First author)
39. Shih-Yi Lee, CY Sheu, CL Wu, CL Hung, YL Weng, CC Lin, WH Chang. Spontaneous Pneumomediastinum: A Clinical-radiologic Analysis. International Journal of Gerontology 2008; 2: 222-8. (IF: 1.016; First author)
Published Articles – Review Articles (* corresponding author)
1. Shih-Yi Lee, Chuan-Lei Cha, Sho-Ting Hung, Hwee-Kheng Lim, Hui-Chun Ku. Airway management in adult vascular central airway obstruction. Signa Vitae 2021; 17: 8 – 17 (IF: 0.907; First author)
2. Umamaheswari Rajaji, Rameshkumar Arumugam, Shen-Ming Chen1, Tse-Wei Chen, Tien-Wen Tseng, Sathishkumar Chinnapaiyan, Shih-Yi Lee*, Wen-Han Chang. Graphene nanoribbons in electrochemical sensors and biosensors: A Review. Int. J. Electrochem Sci. 2018; 13: 6643 – 6654. (IF: 1.765; *corresponding author)
3. Shih-Yi Lee, DK Chien, CH Huang, SC Shih, WC Lee, WH Chang. Dyspnea in pregnancy. Taiwan. J. Obstet. Gynecol. 2017 Aug;56(4):432 – 436. (IF: 2.7; First author)
4. Shih-Yi Lee, Shou-Chuan Shih, Yi-Shing Leu, Wen-Han Chang, Hsin-Chang Lin, Hui-Chun Ku. Implications of age-related changes in anatomy for geriatric-focused difficult airways. International Journal of Gerontology 2017; 11: 130e-133. (IF: 1.016; First author)
5. Shih-Yi Lee, Chih-Hao Chen, Chin-Yin Sheu, Julie Hua Ying Tai, Sheng-Hsiung Yang, Chao-Hsien Chen. The radiological manifestations of the aberrant air surrounding the pleura: In the embryological view. Pulmonary Medicine 2012. Article ID 290802, 8 pages. doi:10.1155/2012/290802. (IF: 1.9; First author)
6. Shih-Yi Lee, CL Hung, JH Lee, SC Shih, YL Weng, WH Chang, YH Ho, WC Huang, YL Lai. Attain Good end-of-life care in intensive care unit in Taiwan- the eilemma and the strategy. International Journal of Gerontology 2009; 3: 26-30. (IF: 1.016; First author)
7. J Gillis, CT Lai, ML Lin, Shih-Yi Lee*. Connecting palliative care and intensive care in Taiwan. International Journal of Gerontology 2008; 2(2): 33-4. (IF: 1.016; *corresponding author)
Published Articles – Editorial (* corresponding author)
1. Hui-Chun Ku, Shih-Yi Lee*. Factors for advancing emergency airway management practice. Signa Vitae 2022; 18: 1 – 4 (IF: 1.1; *corresponding author)
2. Shih-Yi Lee, Ding-Kuo Chien, Sho-Ting Hung, Hui-Chun Ku. Acute respiratory distress syndrome from pulmonary contusion may be a steroid-treatable clinical phenotype of the disease. J Formos Med Assoc. 2021 Mar;120(3):1043-1044. (IF: 3.282; First author)
3. Shih-Yi Lee, Hung ST, Wang KT, Ku HC. Coronary artery fistula presented as a mediastinal mass. J Formos Med Assoc. 2019; 118, 1268-1269. (IF: 3.282; First author)
4. Shih-Yi Lee, Wu CW, Chang WH, Ku HC. Fever and jaundice caused by hemophagocytic syndrome. J Formos Med Assoc. 2019;118(2):649-650. (IF: 3.282; First author)
5. Shih-Yi Lee, Ching-Yu Kuo, Da-Hua Wei, Hui-Chun Ku, Ren-Jei Chung, Wen-Han Chang. Prospective view for mask design. Health Technology 2017; 1: 3. (First author)
Published Articles – Case Reports (* corresponding author)
1. Wei-Cheng Lee, Shou-Chuan Shih, Tsang-En Wang, Cheng-Hsin Chu, Horng-Yuan Wang, Chien-Liang Wu, Hui-Chun Ku, Shih-Yi Lee*. Adrenal insufficiency associated with cholestatic jaundice. International Journal of Gerontology 2018; 12: 164-166. (IF: 1.016; *corresponding author)
2. Chen CH, Chang H, Tai CY, Shih-Yi Lee, Liu HC, Hung TT, Chen CH. Bilateral pulmonary metastectomy through a unilateral single-port thoracoscopic approach. J Thorac Dis. 2014; 6(2): 143-7. (IF: 2.895, Q3)
3. Wu HH, Chen CH, Chang H, Liu HC, Hung TT, Shih-Yi Lee. A preliminary report on the feasibility of single-port thoracoscopic surgery for diaphragm plication in the treatment of diaphragm eventration. J Cardiothorac Surg. 2013 Dec 5;8:224. doi: 10.1186/1749-8090-8-224. (IF: 1.637, Q3)
4. Wei-Chen Lin, Shih-Yi Lee, Li-Kuo Kuo, Horng-Yuan Wang, Ming-Jen Chen. Gastric tube-to-pulmonary fistula after esophagectomy complicated with fatal pulmonary hemorrhage. International Journal of Gerontology 2013, 7: 129-130. (IF: 1.016, Q4)
5. Yueh-Hung Lin, Shou-chuan Shih, Chien-Liang Wu, Yi-Chou Chen, Yu-Wei Chen, Shih-Yi Lee*. Experience of activated protein c in a patient with emphysematous pyelonephritis receiving percutaneous nephrostomy drainage. International Journal of Gerontology 2010; 4(3): 161-164. (IF: 1.016; *corresponding author)
6. SW Huang, CL Wu, CC Lin, CL Hung, LK Kuo, YL Weng, Shih-Yi Lee*. Effect of long term intermittent nocturnal non-invasive positive pressure ventilation on patient with severe kyphoscoliosis and hypoxaemia. BMJ Case Rep. 2009;2009:bcr08.2008.0737. (IF:0.4; *corresponding author)
7. TT Chen, CT Lai, CL Wu, TY Wang, BF Shih, CL Hung, LK Kuo, YL Weng, Shih-Yi Lee*. Cardiac tamponade caused by epithelioid hemangioendothelioma. BMJ Case Rep. 2009; 2009: bcr09.2008.0955. (IF:0.4; *corresponding author)
8. Po-Chin Chi, Chien-Liang Wu, Chung-Lieh Hung, Yu-Ling Weng, Ching-Chi Lin, Shih-Yi Lee*. The experience of a novel of a glycylcycline antibiotic for a patient with infection caused by multiple drug resistant pathogens: what is the benefit? International Journal of Gerontology 2008; 2(3): 124-127. (IF: 1.016; *corresponding author)
9. Shih-Yi Lee, JH Lin, CT Lai, KS Chang and SC Shih. Acute abdomen in post-chemotherapy acute monoblastic leukaemia. International Journal of Gerontology 2007; 1: 164-7. (IF: 1.016; First author)
10. Shih-Yi Lee, KM Wu, PJ Chen, CP Kuo, TY Wang and CL Wu. Intrathoracic tracheal obstruction caused by a carotid mycotic aneurysm in a patient with deep neck infection- a case report. Respiration 2007; 74: 220-3. (IF: 3.580; First author)
11. Shih-Yi Lee. Esophageal gastrointestinal stromal tumor presenting as a mediastinal mass- a case report. Thorac Med 2005; 20: 599-605. (First author)
12. Shih-Yi Lee, HT Kuo, MJ Peng, FJ Lin, SC Shih, CY Sheu and CC Lin. Azygos vein varix mimicking mediastinal mass in a patient with liver cirrhosis: a case report. Chest 2005; 127: 661-4. (IF: 11.93; First author)
Award:
1. 2006 in Japan, Best Poster Award. Asia Pacific Society of Respirology. SY Lee, CL Wu, PJ Chen, CH Lee, FJ Lin. The Changing Hemodynamic Parameters during Weaning from Mechanical Ventilation. Respirology 2006, 11, Suppl 5: A208. http://www.apsresp.org/congress/2006.php#009
2. 2016 in Taiwan. Third Poster Award. Taiwan Society of Geriatric Emergency & Critical Care Medicine. Factors associated with difficult mask ventilation in the emergency department. http://www.sgecm.org.tw/news/news_info.asp?doc-id=280

重症醫學科

重症醫學科

李士毅

現職

主要學歷

主要經歷

主治項目或專長

論文研究